Tuesday, March 20, 2012

Garcinia Cambogia

Garcinia cambogia is a small fruit that resembles a miniature pumpkin. It is indigenous to India and parts of Asia, and an extract from its fruit and rind is popular in many natural weight loss products. The extract is hydroxycitric acid (HCA), claimed to suppress appetite and enhance fat-burning. Animal research supports these claims, but subsequent human trials have been equivocal.

The theory behind garcinia cambogia is that HCA inhibits an enzyme called citrate lyase that helps turns excess carbohydrates into fat. By inhibiting this enzyme, it is believed the body instead boosts carbohydrate oxidation, or simply put, burns the extra carbs. In extensive animal studies, garcinia cambogia was found to reduce food intake by suppressing appetite, as well as to decrease body fat. Human trials have been less clear. While some double-blind studies using garcinia cambogia and a placebo showed the HCA group as doubling or tripling weight loss over a 12-week period as compared to the control group, other studies showed a less promising result.

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Some over-enthusiastic patients who took it in excess found some side effects like diarrhea or some laxative effect, vomiting and abdominal pain.  It has not been studied in pregnant ladies for its safety. So better to avoid it.  Same with breastfeeding mothers.  Testicular atrophy, (when the Ni Ners shrink), is a kind of toxicity that is present only at higher dosage that falls under toxic dosage and not under the therapeutic dose range.  

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